Title : Chronic Glucose Exposure Systematically Shifts the Oscillatory Threshold of Mouse Islets: Experimental Evidence for an Early Intrinsic Mechanism of Compensation for Hyperglycemia.

Pub. Date : 2016 Feb

PMID : 26697721






1 Functional Relationships(s)
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1 Finally, treatment of INS-1 cells with glucose and Dz overnight reduced high affinity sulfonylurea receptor (SUR1) trafficking to the plasma membrane vs glucose alone, consistent with insulin increasing KATP conductance by altering channel number. Glucose ATP binding cassette subfamily C member 8 Rattus norvegicus