Title : DNA Double Strand Break Response and Limited Repair Capacity in Mouse Elongated Spermatids.

Pub. Date : 2015 Dec 16

PMID : 26694360






1 Functional Relationships(s)
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1 Finally, our genetic mutant analysis suggests that an incomplete or defective meiotic recombinational repair of Spo11-induced DSBs may lead to a carry-over of the DSB damage or induce a delayed nuclear fragmentation during the sensitive programmed chromatin remodeling occurring in elongated spermatids. dsbs SPO11 initiator of meiotic double stranded breaks Mus musculus