Pub. Date : 2015
PMID : 26692923
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Lastly, in contrast to both SN-38 (active metabolite of irinotecan) and topotecan are substrates of the efflux pump proteins P-gp/MDR1 and ABCG2/BCRP, FL118 is not a substrate of P-gp and ABCG2. | Irinotecan | phosphoglycolate phosphatase | Homo sapiens |
2 | Lastly, in contrast to both SN-38 (active metabolite of irinotecan) and topotecan are substrates of the efflux pump proteins P-gp/MDR1 and ABCG2/BCRP, FL118 is not a substrate of P-gp and ABCG2. | Irinotecan | phosphoglycolate phosphatase | Homo sapiens |