Title : The Gustatory Signaling Pathway and Bitter Taste Receptors Affect the Development of Obesity and Adipocyte Metabolism in Mice.

Pub. Date : 2015

PMID : 26692363






1 Functional Relationships(s)
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1 Intra-gastric treatment of obese WT and alpha-gust-/- mice with the bitter agonists denatonium benzoate (DB) or quinine (Q) during 4 weeks resulted in an alpha-gustducin-dependent decrease in body weight gain associated with a decrease in food intake (DB), but not involving major changes in gut peptide release. Quinine guanine nucleotide binding protein, alpha transducing 3 Mus musculus