Title : Increased serum levels of C21 steroids in female patients with multiple sclerosis.

Pub. Date : 2015

PMID : 26680486






4 Functional Relationships(s)
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1 Increased serum levels of C21 steroids in female patients with multiple sclerosis. Steroids TBL1X/Y related 1 Homo sapiens
2 Our data show higher levels of circulating C21 steroids including steroid modulators of ionotropic type A gamma-aminobutyric acid (GABA A) receptors and glutamate receptors. Steroids TBL1X/Y related 1 Homo sapiens
3 Our data show higher levels of circulating C21 steroids including steroid modulators of ionotropic type A gamma-aminobutyric acid (GABA A) receptors and glutamate receptors. Steroids TBL1X/Y related 1 Homo sapiens
4 In conclusion, the data demonstrate higher levels of circulating C21 steroids and their polar conjugates and some bioactive C19 steroids in women with MS, which may influence neuronal activity and affect the balance between neuroprotection and excitotoxicity. Steroids TBL1X/Y related 1 Homo sapiens