Title : Resveratrol protects cardiomyocytes from doxorubicin-induced apoptosis through the AMPK/P53 pathway.

Pub. Date : 2016 Feb

PMID : 26675978






4 Functional Relationships(s)
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1 Resveratrol protects cardiomyocytes from doxorubicin-induced apoptosis through the AMPK/P53 pathway. Resveratrol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus
2 The aim of the present study was to investigate the effects of resveratrol on the adenosine monophosphate-activated protein kinase (AMPK)/P53 pathway in mediating DOX-induced cytotoxicity. Resveratrol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus
3 Of note, resveratrol protected against DOX-induced increases of P53 and Bax and also prevented the downregulation of Bcl-2 in H9c2 cells. Resveratrol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus
4 The results of the present study therefore indicated that resveratrol protected H9c2 cells from DOX-induced apoptosis via the AMPK/P53 pathway. Resveratrol Wistar clone pR53P1 p53 pseudogene Rattus norvegicus