Title : Human UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme Inhibition.

Pub. Date : 2016 Mar

PMID : 26669329






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 values for amitriptyline, doxepin, and mianserin inhibition of human liver microsomal UGT2B10 were 0.61 +- 0.05, 0.95 +- 0.18, and 0.43 +- 0.01 microM. Doxepin UDP glucuronosyltransferase family 2 member B10 Homo sapiens