Title : Human β-Defensin 3 [corrected] Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid.

Pub. Date : 2015 Dec

PMID : 26646717






1 Functional Relationships(s)
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1 HBD3 exacerbated the production of type I Interferon-beta in response to the viral ligand mimic polyinosinic:polycytidylic acid (polyI:C) in both human and mouse primary cells, although production of the chemokine CXCL10 was suppressed. Poly C interferon beta 1, fibroblast Mus musculus