Pub. Date : 2016 Mar
PMID : 26645913
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Stimulation of NHBE cells with recombinant TNF-alpha increased both MUC1 and EGFR protein levels, and stimulation of these cells with Pa enhanced MUC1-CT tyrosine phosphorylation and increased MUC1-CT/TLR5 and MUC1-CT/EGFR protein association, in an EGFR-dependent manner. | Tyrosine | mucin 1, cell surface associated | Homo sapiens |
| 2 | Stimulation of NHBE cells with recombinant TNF-alpha increased both MUC1 and EGFR protein levels, and stimulation of these cells with Pa enhanced MUC1-CT tyrosine phosphorylation and increased MUC1-CT/TLR5 and MUC1-CT/EGFR protein association, in an EGFR-dependent manner. | Tyrosine | mucin 1, cell surface associated | Homo sapiens |
| 3 | Stimulation of NHBE cells with recombinant TNF-alpha increased both MUC1 and EGFR protein levels, and stimulation of these cells with Pa enhanced MUC1-CT tyrosine phosphorylation and increased MUC1-CT/TLR5 and MUC1-CT/EGFR protein association, in an EGFR-dependent manner. | Tyrosine | mucin 1, cell surface associated | Homo sapiens |
| 4 | CONCLUSIONS: These results indicate that in response to Pa or flagellin, EGFR associates with and tyrosine phosphorylates MUC1-CT in primary NHBE cells, leading to increased MUC1-CT association with TLR5. | Tyrosine | mucin 1, cell surface associated | Homo sapiens |
| 5 | CONCLUSIONS: These results indicate that in response to Pa or flagellin, EGFR associates with and tyrosine phosphorylates MUC1-CT in primary NHBE cells, leading to increased MUC1-CT association with TLR5. | Tyrosine | mucin 1, cell surface associated | Homo sapiens |