Title : Characterization of Motor Neuron Prostaglandin E2 EP3 Receptor Isoform in a Mouse Model of Amyotrophic Lateral Sclerosis.

Pub. Date : 2015

PMID : 26632188






1 Functional Relationships(s)
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1 These results suggest that the PGE2-to-EP3 signaling pathway is mediated mainly by the EP3gamma isoform in the motor neurons of mice, and that modulation of the EP3gamma isoform in motor neurons may be a promising new therapeutic approach for ALS. Dinoprostone prostaglandin E receptor 3 (subtype EP3) Mus musculus