Pub. Date : 2016 May 8
PMID : 26625977
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | DSBs promote rapid accumulation of repressive complexes, including HP1, the NuRD complex, H2A.Z and histone methyltransferases at the DSB. | dsbs | H2A.Z variant histone 1 | Homo sapiens |
| 2 | H2A.Z removal at DSBs alters the acidic patch on the nucleosome surface, promoting acetylation of the H4 tail (by the NuA4-Tip60 complex) and shifting the chromatin to a more open structure. | dsbs | H2A.Z variant histone 1 | Homo sapiens |