Title : Changes in plasma concentrations of corticosterone and its precursors after ketoconazole administration in rats: An application of simultaneous measurement of multiple steroids using LC-MS/MS.

Pub. Date : 2016 Feb-Mar

PMID : 26610754






1 Functional Relationships(s)
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1 The changes in the adrenal gland and plasma concentration of steroids were thought to reflect inhibited metabolism of deoxycorticosterone to corticosterone through inhibition of CYP11B1, and compensatory reaction for the inhibition. Desoxycorticosterone cytochrome P450, family 11, subfamily b, polypeptide 1 Rattus norvegicus