Title : Identification of polymorphic variants associated with erlotinib-related skin toxicity in advanced non-small cell lung cancer patients by DMET microarray analysis.

Pub. Date : 2016 Jan

PMID : 26607259






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1 CONCLUSION: Although exploratory, this study indicates rs8176345 in CYP27B1 gene as significantly correlated with erlotinib-induced SR in aNSCLC patients probably through a mechanism mediated by vitamin D3 and inflammation at skin level. Cholecalciferol cytochrome P450 family 27 subfamily B member 1 Homo sapiens