Title : Tumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy.

Pub. Date : 2015

PMID : 26604751






3 Functional Relationships(s)
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1 METHODS: GNR-Dox-Tf-NPs (gold nanorod-doxorubicin-transferrin-nanoparticles) were prepared by different chemical approaches. Doxorubicin transferrin Homo sapiens
2 METHODS: GNR-Dox-Tf-NPs (gold nanorod-doxorubicin-transferrin-nanoparticles) were prepared by different chemical approaches. Doxorubicin transferrin Homo sapiens
3 RESULTS: We developed and tested a gold nanorod-based multifunctional nanoparticle system (GNR-Dox-Tf-NP) that carries Dox conjugated to a pH-sensitive linker and is targeted to the transferrin receptor overexpressed in human lung cancer (A549, HCC827) cells. Doxorubicin transferrin Homo sapiens