Title : H295R expression of melanocortin 2 receptor accessory protein results in ACTH responsiveness.

Pub. Date : 2016 Feb

PMID : 26576642






2 Functional Relationships(s)
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1 Treatment with ACTH significantly increased aldosterone, cortisol, and dehydroepiandrosterone production in H295RA cells. Dehydroepiandrosterone proopiomelanocortin Homo sapiens
2 ACTH also significantly increased transcript levels for all of the steroidogenic enzymes required to produce aldosterone, cortisol, and dehydroepiandrosterone, as well as MC2R mRNA. Dehydroepiandrosterone proopiomelanocortin Homo sapiens