Pub. Date : 2016 Mar
PMID : 26576483
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Pathway analysis revealed that elevated c-myc expression and ethanol uptake synergistically lead to strong AKT activation, Mdm2 phosphorylation and as a consequence to inhibition of p53. | Ethanol | tumor protein p53 | Homo sapiens |
2 | CONCLUSIONS: Expression of c-myc and EtOH-uptake synergistically accelerate the progression of ALD most likely due to loss of p53-dependent protection. | Ethanol | tumor protein p53 | Homo sapiens |