Title : Effect of Genistein and L-Carnitine and Their Combination on Gene Expression of Hepatocyte HMG-COA Reductase and LDL Receptor in Experimental Nephrotic Syndrome.

Pub. Date : 2015 Oct

PMID : 26576346






3 Functional Relationships(s)
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1 Effect of Genistein and L-Carnitine and Their Combination on Gene Expression of Hepatocyte HMG-COA Reductase and LDL Receptor in Experimental Nephrotic Syndrome. Genistein 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
2 In the present study, we have delved into the separate and the twin-effects of L-carnitine and genistein on the gene expressions of HMG-COA reductase and LDL receptor in experimental nephrotic syndrome. Genistein 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens
3 CONCLUSION: This study shows a significant decreasing (P<0.001) and non-significant increasing trend in HMG-COA Reductase and LDLr gene expression, respectively, and synergistic effect of L-carnitine and genistein on these genes in experimental nephrotic syndrome. Genistein 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens