Title : Lico A Enhances Nrf2-Mediated Defense Mechanisms against t-BHP-Induced Oxidative Stress and Cell Death via Akt and ERK Activation in RAW 264.7 Cells.

Pub. Date : 2015

PMID : 26576227






2 Functional Relationships(s)
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1 Lico A Enhances Nrf2-Mediated Defense Mechanisms against t-BHP-Induced Oxidative Stress and Cell Death via Akt and ERK Activation in RAW 264.7 Cells. tert-Butylhydroperoxide nuclear factor, erythroid derived 2, like 2 Mus musculus
2 Therefore, Lico A might have a protective role against t-BHP-induced cytotoxicity by modulating HO-1 and by scavenging ROS via the activation of the PI3K/Akt and ERK/Nrf2 signaling pathways. tert-Butylhydroperoxide nuclear factor, erythroid derived 2, like 2 Mus musculus