Title : Novel Activities of Select NSAID R-Enantiomers against Rac1 and Cdc42 GTPases.

Pub. Date : 2015

PMID : 26558612






1 Functional Relationships(s)
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1 Based on high throughput screening of the Prestwick Chemical Library and cheminformatics we identified the R-enantiomers of two approved drugs (naproxen and ketorolac) as inhibitors of Rac1 and Cdc42. Naproxen Rac family small GTPase 1 Homo sapiens