Title : Cisplatin-mediated cytotoxicity through inducing CYP4A 11 expression in human renal tubular epithelial cells.

Pub. Date : 2015 Dec

PMID : 26558470






3 Functional Relationships(s)
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1 20-Hydroxyeicosatetraenoic acid (20-HETE) is a CYP4A11 metabolite of arachidonic acid that plays an important role in renal injury. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily A member 11 Homo sapiens
2 20-Hydroxyeicosatetraenoic acid (20-HETE) is a CYP4A11 metabolite of arachidonic acid that plays an important role in renal injury. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily A member 11 Homo sapiens
3 Results showed that 20-HETE (1, 10, 50 muM), a CYP4A11 metabolite of arachidonic acid, significantly increased lactate dehydrogenase (LDH) release in these cells. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily A member 11 Homo sapiens