Title : Ribavirin contributes to eradicate hepatitis C virus through polarization of T helper 1/2 cell balance into T helper 1 dominance.

Pub. Date : 2015 Nov 8

PMID : 26557951






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 RBV up-regulates type 1 and/or 2 cytokines to modulate the T helper (Th) 1/2 cell balance to Th1 dominance. Ribavirin negative elongation factor complex member C/D Homo sapiens
2 These findings indicate that RBV mainly down-regulates the activity of Th2 cells, resulting in the maintenance of Th1 activity that contributes to abrogating HCV-infected hepatocytes. Ribavirin negative elongation factor complex member C/D Homo sapiens