Title : Cleavage of Signal Regulatory Protein α (SIRPα) Enhances Inflammatory Signaling.

Pub. Date : 2015 Dec 25

PMID : 26534964






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SIRPalpha ligation by a broadly expressed transmembrane protein, CD47, results in phosphorylation of the cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, resulting in the inhibition of NF-kappaB signaling in macrophages. Tyrosine CD47 molecule Homo sapiens