Title : MicroRNA-21 induces breast cancer cell invasion and migration by suppressing smad7 via EGF and TGF-β pathways.

Pub. Date : 2016 Jan

PMID : 26531758






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1 Moreover, miR-21, EGF and TGF-beta combined to markedly increase cancer cell invasion and migration, and this effect was blocked by the combination of erlotinib (an EGF receptor kinase inhibitor) and SB505124 (a type I TGF-beta receptor inhibitor). Erlotinib Hydrochloride microRNA 21 Homo sapiens