Pub. Date : 2015 Dec
PMID : 26522688
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We found that aspirin significantly down-regulated TfR1, while also up-regulated Fpn1 and ferritin expressions in BV-2 microglial cells in vitro. | Aspirin | transferrin receptor | Mus musculus |
2 | We also showed that TfR1 and Fpn1 expressions were significantly higher, while ferritin contents, IL-6, TNF-alpha and hepcidin mRNA levels were lower in cells treated with aspirin plus LPS than those in cells treated with LPS only. | Aspirin | transferrin receptor | Mus musculus |
3 | Our findings also suggested that hepcidin might play a dominant role in the control of TfR1 expression by aspirin in the cells treated with LPS. | Aspirin | transferrin receptor | Mus musculus |