Title : Effect of bovine ABCG2 polymorphism Y581S SNP on secretion into milk of enterolactone, riboflavin and uric acid.

Pub. Date : 2016 Feb

PMID : 26510964






2 Functional Relationships(s)
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1 The in vitro ABCG2-mediated transport of the drug mitoxantrone, as a model substrate, was inhibited by enterolactone in both variants, suggesting the possible in vivo use of this enterolignan to reduce ABCG2-mediated milk drug transfer in cows. enterolignan ATP binding cassette subfamily G member 2 Bos taurus
2 The in vitro ABCG2-mediated transport of the drug mitoxantrone, as a model substrate, was inhibited by enterolactone in both variants, suggesting the possible in vivo use of this enterolignan to reduce ABCG2-mediated milk drug transfer in cows. enterolignan ATP binding cassette subfamily G member 2 Bos taurus