Pub. Date : 2015 Dec 1
PMID : 26508549
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Finally, we have observed that alpha-mangostin selectively promotes demethylation of 5-methylcytosine (5mC) and histone H3 trimethylated lysine residues in IDH1 (+/R132H) MCF10A cells, presumably via restoring the activity of cellular alpha-KG-dependent DNA hydroxylases and histone H3 lysine demethylases. | Lysine | isocitrate dehydrogenase (NADP(+)) 1 | Homo sapiens |