Title : [Anti-cancer drug resistance and glutathione S-transferases].

Pub. Date : 1989 Mar

PMID : 2650631






1 Functional Relationships(s)
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1 Most of them, especially alkylating agents, are conjugated with GSH by GSTs and detoxified, and the peroxides from drugs such as adriamycin are also reduced with GSH and detoxified by the GSH peroxidase activity of certain GST forms. Doxorubicin hematopoietic prostaglandin D synthase Rattus norvegicus