Pub. Date : 2016 May
PMID : 26502925
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Second, the administration of rosuvastatin or the combination of two drugs decreased MAPK/ERK signaling and MMP-9 levels, and the suppression of miR-497 upregulated these levels. | Rosuvastatin Calcium | mitogen-activated protein kinase 1 | Mus musculus |
| 2 | Second, the administration of rosuvastatin or the combination of two drugs decreased MAPK/ERK signaling and MMP-9 levels, and the suppression of miR-497 upregulated these levels. | Rosuvastatin Calcium | mitogen-activated protein kinase 1 | Mus musculus |
| 3 | Third, the administration of rosuvastatin or the combination of two drugs increased miR-497 expression levels in the aortas of apoE knockout mice, but the levels of serum lipids and plaque areas decreased, which improved plaque components and decreased the MAPK/ERK signaling and MMP-9 levels. | Rosuvastatin Calcium | mitogen-activated protein kinase 1 | Mus musculus |
| 4 | Third, the administration of rosuvastatin or the combination of two drugs increased miR-497 expression levels in the aortas of apoE knockout mice, but the levels of serum lipids and plaque areas decreased, which improved plaque components and decreased the MAPK/ERK signaling and MMP-9 levels. | Rosuvastatin Calcium | mitogen-activated protein kinase 1 | Mus musculus |