Title : Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes.

Pub. Date : 2016 Jan 1

PMID : 26494904






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 This was most extensive in SU5402 and AZD1480, which inhibited DDR2, IGF1R, FLT3, TRKA, FLT4, ABL and JAK3 with efficiencies similar to or greater than those for FGFR. AZD 1480 fms related receptor tyrosine kinase 4 Homo sapiens