Title : MET18 Connects the Cytosolic Iron-Sulfur Cluster Assembly Pathway to Active DNA Demethylation in Arabidopsis.

Pub. Date : 2015 Oct

PMID : 26492035






3 Functional Relationships(s)
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1 Site-directed mutagenesis of ROS1 indicated that the conserved iron-sulfur motif is indispensable for ROS1 enzymatic activity. Iron demeter-like 1 Arabidopsis thaliana
2 Site-directed mutagenesis of ROS1 indicated that the conserved iron-sulfur motif is indispensable for ROS1 enzymatic activity. Iron demeter-like 1 Arabidopsis thaliana
3 Our results suggest that ROS1-mediated active DNA demethylation requires MET18-dependent transfer of the iron-sulfur cluster, highlighting an important role of the CIA pathway in epigenetic regulation. Iron demeter-like 1 Arabidopsis thaliana