Title : Cryptotanshinone and wogonin up-regulate eNOS in vascular endothelial cells via ERα and down-regulate iNOS in LPS stimulated vascular smooth muscle cells via ERβ.

Pub. Date : 2016 Feb

PMID : 26481132






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cryptotanshinone and wogonin up-regulate eNOS in vascular endothelial cells via ERalpha and down-regulate iNOS in LPS stimulated vascular smooth muscle cells via ERbeta. cryptotanshinone estrogen receptor 1 Homo sapiens
2 In EA.hy926 cells, treatment of cryptotanshinone and wogonin led to significant increase in NO production levels, which were inhibited by co-incubation of estrogen receptor (ER)alpha antagonist methyl-piperidino-pyrazole (MPP). cryptotanshinone estrogen receptor 1 Homo sapiens
3 In EA.hy926 cells, treatment of cryptotanshinone and wogonin led to significant increase in NO production levels, which were inhibited by co-incubation of estrogen receptor (ER)alpha antagonist methyl-piperidino-pyrazole (MPP). cryptotanshinone estrogen receptor 1 Homo sapiens