Title : The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain.

Pub. Date : 2016 Jun 23

PMID : 26477317






1 Functional Relationships(s)
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1 A fine characterization of the DNA deformation caused by p53 binding is obtained, with "static" deformations always present and measured by the slide parameter in the central thymine-adenine base pairs; we also detect "dynamic" deformations switched on and off by particular p53 tetrameric conformations and measured by the roll and twist parameters in the same base pairs. Thymine tumor protein p53 Homo sapiens