Title : Celecoxib antagonizes the cytotoxicity of oxaliplatin in human esophageal cancer cells by impairing the drug influx.

Pub. Date : 2016 Jan 1

PMID : 26474693






3 Functional Relationships(s)
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1 Celecoxib alone or combined with oxaliplatin substantially reduced the expression of organic cation transporter 2 (OCT2). Celecoxib solute carrier family 22 member 2 Homo sapiens
2 Celecoxib alone or combined with oxaliplatin substantially reduced the expression of organic cation transporter 2 (OCT2). Celecoxib solute carrier family 22 member 2 Homo sapiens
3 To conclude, our data provide evidence that the addition of celecoxib to oxaliplatin-containing regimens for patients with OCT2-expressing cancers should be cautious. Celecoxib solute carrier family 22 member 2 Homo sapiens