Pub. Date : 2015 Dec 1
PMID : 26467186
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The 3-h exposure of MMECs to metformin significantly (P<0.05) reversed the HG-induced reduction in phosphorylation of both eNOS and Akt; however, no changes were detected for phosphorylation of AMPK or the expression of SIRT1. | Metformin | thymoma viral proto-oncogene 1 | Mus musculus |
2 | Our data indicate that a 3-h exposure to metformin can reverse/reduce the impact of HG on endothelial function, via mechanisms linked to increased phosphorylation of eNOS and Akt. | Metformin | thymoma viral proto-oncogene 1 | Mus musculus |