Title : Mechanisms of dihydrotestosterone action on resveratrol-induced anti-proliferation in breast cancer cells with different ERĪ± status.

Pub. Date : 2015 Nov 3

PMID : 26456774






8 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Resveratrol induces p53-dependent apoptosis via plasma membrane integrin alphavbeta3. Resveratrol tumor protein p53 Homo sapiens
2 DHT inhibited resveratrol-stimulated phosphorylation of Ser-15 of p53 in a concentration-dependent manner. Resveratrol tumor protein p53 Homo sapiens
3 DHT inhibited resveratrol-induced nuclear complex of p53-COX-2 formation which is required p53-dependent apoptosis. Resveratrol tumor protein p53 Homo sapiens
4 DHT inhibited resveratrol-induced nuclear complex of p53-COX-2 formation which is required p53-dependent apoptosis. Resveratrol tumor protein p53 Homo sapiens
5 ChIP studies of COX-2/p53 binding to DNA and expression of p53-responsive genes indicated that DHT inhibited resveratrol-induced p53-directed transcriptional activity. Resveratrol tumor protein p53 Homo sapiens
6 ChIP studies of COX-2/p53 binding to DNA and expression of p53-responsive genes indicated that DHT inhibited resveratrol-induced p53-directed transcriptional activity. Resveratrol tumor protein p53 Homo sapiens
7 ChIP studies of COX-2/p53 binding to DNA and expression of p53-responsive genes indicated that DHT inhibited resveratrol-induced p53-directed transcriptional activity. Resveratrol tumor protein p53 Homo sapiens
8 In addition, DHT did inhibit resveratrol-induced COX-2/p53-dependent gene expression. Resveratrol tumor protein p53 Homo sapiens