Title : Rebamipide Suppresses Monosodium Urate Crystal-Induced Interleukin-1β Production Through Regulation of Oxidative Stress and Caspase-1 in THP-1 Cells.

Pub. Date : 2016 Feb

PMID : 26454448






3 Functional Relationships(s)
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1 Rebamipide Suppresses Monosodium Urate Crystal-Induced Interleukin-1beta Production Through Regulation of Oxidative Stress and Caspase-1 in THP-1 Cells. rebamipide caspase 1 Homo sapiens
2 Rebamipide also attenuated enhanced expression of caspase-1 gene by MSU crystals (p < 0.05). rebamipide caspase 1 Homo sapiens
3 This study demonstrated that rebamipide inhibits IL-1beta activation through suppression of ROS-mediated NF-kappaB signaling pathways and caspase-1 activation in MSU crystal-induced inflammation. rebamipide caspase 1 Homo sapiens