Pub. Date : 2016 Jan
PMID : 26447367
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activated by Norgestrel through nuclear trafficking, siRNA knock down of PGRMC1 abrogated the protective properties of Norgestrel on damaged photoreceptors. | Norgestrel | progesterone receptor membrane component 1 | Mus musculus |
| 2 | Activated by Norgestrel through nuclear trafficking, siRNA knock down of PGRMC1 abrogated the protective properties of Norgestrel on damaged photoreceptors. | Norgestrel | progesterone receptor membrane component 1 | Mus musculus |
| 3 | Furthermore, specific inhibition of PGRMC1 by AG205 blocked Norgestrel-induced protection in stressed retinal explants. | Norgestrel | progesterone receptor membrane component 1 | Mus musculus |
| 4 | Therefore, we conclude that PGRMC1 is crucial to the neuroprotective effects of Norgestrel on stressed photoreceptors. | Norgestrel | progesterone receptor membrane component 1 | Mus musculus |