Title : Mechanism of QSYQ on anti-apoptosis mediated by different subtypes of cyclooxygenase in AMI induced heart failure rats.

Pub. Date : 2015 Oct 7

PMID : 26445960






3 Functional Relationships(s)
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1 Moreover, RT-PCR showed that expressions of EP2 and EP4, which are the receptors of PGE2, were also up-regulated. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus
2 Increased expressions of apoptotic pathway factors, including P53 and FasL, might be induced by the binding of PGE2 with EP2/4. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus
3 Expressions of EP2 and EP4 receptors also decreased, suggesting that PGE2-mediated apoptosis was inhibited by QSYQ. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus