Title : The role of adenosine and prostacyclin in coronary flow regulation in healthy man.

Pub. Date : 1989 Jan

PMID : 2643255






2 Functional Relationships(s)
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1 Theophylline, at a dose blocking the coronary flow response to dipyridamole (an adenosine-dependent mechanism), induced a moderate increase in myocardial oxygen extraction (by 11%, P less than 0.05), but failed to affect either the basal coronary flow (105 +/- 16 ml min-1) or the increase during exercise (88 +/- 25 ml min-1). Adenosine CD59 molecule (CD59 blood group) Homo sapiens
2 Theophylline, at a dose blocking the coronary flow response to dipyridamole (an adenosine-dependent mechanism), induced a moderate increase in myocardial oxygen extraction (by 11%, P less than 0.05), but failed to affect either the basal coronary flow (105 +/- 16 ml min-1) or the increase during exercise (88 +/- 25 ml min-1). Adenosine CD59 molecule (CD59 blood group) Homo sapiens