Title : Pleiotropic effects of statins.

Pub. Date : 2015 Sep-Oct

PMID : 26425463






1 Functional Relationships(s)
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1 Statins or 3-hydroxy-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors not only prevents the synthesis of cholesterol biosynthesis but also inhibits the synthesis of essential isoprenoid intermediates such as farnesyl pyrophosphate, geranylgeranyl pyrophosphate, isopentanyl adenosine, dolichols and polyisoprenoid side chains of ubiquinone, heme A, and nuclear lamins. farnesyl pyrophosphate 3-hydroxy-3-methylglutaryl-CoA reductase Homo sapiens