Title : Structure and mechanism of the mammalian fructose transporter GLUT5.

Pub. Date : 2015 Oct 15

PMID : 26416735






2 Functional Relationships(s)
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1 On the basis of a comparison of the inward-facing structures of GLUT5 and human GLUT1, a ubiquitous glucose transporter, we show that a single point mutation is enough to switch the substrate-binding preference of GLUT5 from fructose to glucose. Fructose solute carrier family 2 member 5 Homo sapiens
2 On the basis of a comparison of the inward-facing structures of GLUT5 and human GLUT1, a ubiquitous glucose transporter, we show that a single point mutation is enough to switch the substrate-binding preference of GLUT5 from fructose to glucose. Fructose solute carrier family 2 member 5 Homo sapiens