Pub. Date : 2015 Nov 7
PMID : 26414088
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Halogenated quinolines discovered through reductive amination with potent eradication activities against MRSA, MRSE and VRE biofilms. | Quinolines | solute carrier family 9 member A6 | Homo sapiens |
2 | Here, we report the discovery of several halogenated quinolines (HQs) identified through a reductive amination reaction that demonstrated potent eradication of MRSA (HQ-6; MBEC = 125 muM), MRSE (HQ-3; MBEC = 3.0 muM) and VRE (HQ-4, HQ-5 and HQ-6; MBEC = 1.0 muM) biofilms. | Quinolines | solute carrier family 9 member A6 | Homo sapiens |