Title : Base damage, local sequence context and TP53 mutation hotspots: a molecular dynamics study of benzo[a]pyrene induced DNA distortion and mutability.

Pub. Date : 2015 Oct 30

PMID : 26400171






1 Functional Relationships(s)
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1 Using TP53 trinucleotide mutation signatures for lung cancer in smokers and non-smokers we further show that codons 157 and 273 have the highest mutation probability in smokers. trinucleotide tumor protein p53 Homo sapiens