Pub. Date : 2016 Feb
PMID : 26394716
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arabinoxylan activates Dectin-1 and modulates particulate beta-glucan-induced Dectin-1 activation. | arabinoxylan | C-type lectin domain containing 7A | Homo sapiens |
| 2 | Arabinoxylan activates Dectin-1 and modulates particulate beta-glucan-induced Dectin-1 activation. | arabinoxylan | C-type lectin domain containing 7A | Homo sapiens |
| 3 | METHODS AND RESULTS: By applying reporter cell lines for Toll-like receptors (TLRs) and Dectin-1, we demonstrated that arabinoxylan interacts with Dectin-1 receptors and not with TLRs. | arabinoxylan | C-type lectin domain containing 7A | Homo sapiens |
| 4 | METHODS AND RESULTS: By applying reporter cell lines for Toll-like receptors (TLRs) and Dectin-1, we demonstrated that arabinoxylan interacts with Dectin-1 receptors and not with TLRs. | arabinoxylan | C-type lectin domain containing 7A | Homo sapiens |
| 5 | Arabinoxylan activates Dectin-1 to a similar magnitude as soluble beta-glucans. | arabinoxylan | C-type lectin domain containing 7A | Homo sapiens |
| 6 | As arabinoxylan is also soluble, the inhibiting capacity of arabinoxylan on particulate beta-glucan-activated Dectin-1 cell lines was studied. | arabinoxylan | C-type lectin domain containing 7A | Homo sapiens |
| 7 | The Dectin-1 inhibitory function of arabinoxylan was further confirmed in human dendritic cells that demonstrated reduced production of IL-10 and TNF-alpha. | arabinoxylan | C-type lectin domain containing 7A | Homo sapiens |
| 8 | CONCLUSION: Arabinoxylan activates Dectin-1 and supports antifungal immune responses in human dendritic cells. | arabinoxylan | C-type lectin domain containing 7A | Homo sapiens |