Title : Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins.

Pub. Date : 2015 Dec

PMID : 26374172






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A detailed kinetic analysis coupled with absolute quantification of membrane transporter proteins by liquid chromatography-tandem mass spectrometry revealed that atenolol is an excellent substrate for the renal transporters hOCT2, hMATE1, and hMATE2-K. Atenolol solute carrier family 47 member 1 Homo sapiens
2 The overall permeability of atenolol in the B-to-A direction in hOCT2/hMATE1 cells was 44-fold higher than in control cells. Atenolol solute carrier family 47 member 1 Homo sapiens