Pub. Date : 2016 Feb
PMID : 26373430
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When AMPK was activated by AICAR, A769662 and metformin, FcepsilonRI-mediated Syk, ERK, JNK and p38 activation, and TNFalpha release were all inhibited. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 2 | In vivo, AMPK activation by metformin could readily reduce vascular permeability and ear swelling in a mouse model of passive cutaneous anaphylaxis mediated by IgE. | Metformin | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |