Title : miR-506: a regulator of chemo-sensitivity through suppression of the RAD51-homologous recombination axis.

Pub. Date : 2015 Sep 14

PMID : 26369335






2 Functional Relationships(s)
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1 Further functional study demonstrated that miR-506 could augment the response to cisplatin and olaparib through targeting RAD51 and suppressing homologous recombination in a panel of ovarian cancer cell lines. Cisplatin microRNA 506 Homo sapiens
2 Systemic delivery of miR-506 in an orthotopic ovarian cancer mouse model significantly augmented the cisplatin response, thus recapitulating the clinical observation. Cisplatin microRNA 506 Homo sapiens