Pub. Date : 2015 Sep 14
PMID : 26365427
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation. | TH9 | forkhead box P3 | Homo sapiens |
| 2 | Furthermore, GITR ligation also activates STAT6, and STAT6 renders Il9 locus accessible via recruitment of histone acetyltransferase p300, and together with inhibition of Foxp3, GITR induces strong Th9 responses. | TH9 | forkhead box P3 | Homo sapiens |