Title : Stamping out RAF and MEK1/2 to inhibit the ERK1/2 pathway: an emerging threat to anticancer therapy.

Pub. Date : 2016 May 19

PMID : 26364606






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 They were not efficiently targeted by the first-generation inhibitors such as Lonafarnib or Sorafenib, which were essentially broad spectrum inhibitors targeting pan-RAS and pan-RAF, respectively. Sorafenib zinc fingers and homeoboxes 2 Homo sapiens