Title : Targeted inhibition of mitochondrial Hsp90 induces mitochondrial elongation in Hep3B hepatocellular carcinoma cells undergoing apoptosis by increasing the ROS level.

Pub. Date : 2015 Nov

PMID : 26351876






1 Functional Relationships(s)
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1 Previous studies reported that a Gamitrinib variant containing triphenylphosphonium (G-TPP) binds to mitochondrial Hsp90 and rapidly inhibits its activity to induce apoptosis. Gamitrinib heat shock protein 90 alpha family class A member 1 Homo sapiens